Engineered Bacteria Paint Targets on Tumors for Cancer-killing T Cells to See
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Columbia engineers are the first to program bacteria to act as beacons that guide the activity of engineered T cells. This work is also the first to design interactions between these two “living” medicines to enable targeting of a broad range of solid tumors.
Evelyn Zilch on LinkedIn: Engineered Bacteria Paint Targets on
Treating tumors with engineered dendritic cells
The immunostimulatory RNA RN7SL1 enables CAR-T cells to enhance
Microbial Cocoon Helps Cells Penetrate, Shrink Tumors
Exploding cancer cells can cause side effects in CAR-T cell
T Cells, Immunophenotyping of T-Cells
Publications — Synthetic Biological Systems Laboratory
Engineered Bacteria Make Tumors More T Cell-Friendly
Bacterial-Based Methods for Cancer Treatment: What We Know and
Engineered bacteria guide CAR-T cells to poorly infiltrated solid
How to engineer bacteria to treat cancer - Mapping Ignorance
Engineering bacteria as interactive cancer therapies
